Serotonin syndrome is an iatrogenic disorder induced by pharmacologic treatment with serotonergic agents that increases serotonin activity. In addition, there is a wide variety of clinical disorders associated with serotonin excess. The frequent concurrent use of serotonergic and neuroleptic drugs and similarities between serotonin syndrome and neuroleptic malignant syndrome can present the clinician with a diagnostic challenge. In this article, we review the pathophysiology, diagnosis, and treatment of serotonin syndrome as well as other serotonergic disorders.
Full article – https://academic.oup.com/painmedicine/article/4/1/63/1816666
An important debate on Antidepressants occurred at the Senedd/Assembly on Wednesday 22nd May 2019.
Wales is truly at the forefront of the battle to help raise awareness to the adverse effects.
Video available here
(At 2:15 in)
Stevens-Johnson syndrome is a rare but serious disorder that affects the skin, mucous membrane, genitals and eyes.
The mucous membrane is the soft layer of tissue that lines the digestive system from the mouth to the anus, as well as the reproductive organs and eyeballs.
It is usually caused by an unpredictable adverse reaction to certain medications. It can also sometimes be caused by an infection.
The syndrome often begins with flu-like symptoms, followed by a red or purple rash that spreads and forms blisters. The affected skin eventually dies and peels off.
Stevens-Johnson syndrome is a medical emergency that requires treatment in hospital, often in intensive or a burns unit.
- feeling generally unwell
- high temperature
- joint pain
- a cough
- a rash that looks like a target
- facial swelling
- crusty sores and blistering
Hospital treatment is required immediately.
Treatment while in hospital may include:
- strong painkillers
- cold compress against the skin
- moisturising affected skin
- fluid replacement
- eye drops and ointment
Girl left covered in burns and blisters that glued her eyes shut after suffering allergic reaction to PAINKILLERS