Man found dead in bed by his mother was in ‘constant pain’ before he died

A MAN found dead in bed by his mother on December 5 last year was in constant pain due to health problems, an inquest was told.

Jeffrey Lloyd, 59, of Pontypool, lived with his mother, Margaret, and took medication including morphine to ease the pain of spinal stenosis. He suffered from asthma and bronchitis, smoked cannabis for pain relief, and was dependant on alcohol, said Mrs Lloyd in a statement.

She had checked him and found him asleep at around 3am that morning, but he was not breathing when she checked again at 5.10am

A post mortem examination determined the cause of death as acute exacerbation of chronic obstructive pulmonary disease (COPD) – though Mrs Lloyd said he had not been diagnosed with it – and alcohol and drugs intake. Several prescribed drugs were detected in his system, in therapeutic doses.

Senior coroner for Gwent Wendy James said that together these produced a “cocktail”. She recorded a narrative conclusion, that Mr Lloyd died of natural causes, exacerbated by alcohol and drugs intake.

Full article: http://www.southwalesargus.co.uk/news/16397839.man-found-dead-in-bed-by-his-mother-was-in-constant-pain-before-he-died/

Withdrawal – What we Know and Don’t Know

Antidepressant Withdrawal – What we Know and Don’t Know

My Doctor/Psychiatrist told me that I have to take an antidepressant to correct a
chemical imbalance in my brain, is this true?

No, it is a myth, we cannot test or measure the state of neurotransmitters in your brain, the
American Psychiatric Association disavowed this myth in 2011(1). It is a pharmaceutical
company invention (2).

How many people experience withdrawal effects?

It varies according to which drug is used, at what dosage, and for how long. Recent
studies (3) are showing the number affected to be greater than 50% of those taking the
drugs. The UK Royal College of Psychiatrists did their own survey (4) (now removed) which
showed that 63% reported withdrawal effects.

Why does my doctor/psychiatrist keep saying ‘discontinuation syndrome’ when I
mention withdrawal?

Discontinuation syndrome is an invented term (5) which minimises the role of the drug in the
harm caused and steers users away from addiction terminology. While dependence and
withdrawal have some features in common with addiction, they are not accurately
described using just this approach. What you are experiencing is an effect of withdrawing
from a drug, not of discontinuing treatment.

Why does my doctor insist that ‘once the drug is out of my system’ I will be fine?

Because not all doctors understand the effects of antidepressant drugs on the brain (6). A
heavy drinker or smoker may suddenly stop drinking/smoking, but the effects on their brain
and nervous system continue to be felt long after they have quit. Antidepressant drugs
change the brain in ways we don’t currently understand. These adaptations (7) to the drug
are responsible for withdrawal effects.

What does withdrawal feel like?

It’s a highly variable experience ranging from mild symptoms which pass quickly, to
profound symptoms that sometimes persist for many years. In a 2017 survey (8), 46% of
those reporting withdrawal symptoms described them as ‘severe’. Most common reported
symptoms (9) are insomnia, dizziness, fatigue, digestive problems, anxiety, panic,
depression, agitation. Withdrawal symptoms can sometimes mimic depressive or anxious states but should not be confused with relapse (10).

I am worried about dependence, what should I do?

The most important thing is never stop your drugs suddenly, this can be dangerous. Talk to
your doctor but be prepared as many doctors do not have the information to be able to
help. Withdrawal is a unique experience, with no fixed rules.

There are some excellent and
reliable online sources for help including:
• theinnercompass.org
• madinamerica.com/drug-withdrawal-resources
• survivingantidepressants.org
www.jfmoore.co.uk August, 2018
Antidepressant Withdrawal – What we Know and Don’t Know

References (to read these online visit www.jfmoore.co.uk/ltw.html)
1. http://www.psychiatrictimes.com/blogs/couch-crisis/psychiatry-new-brain-mind-andlegend-chemical-imbalance
2. https://www.scientificamerican.com/article/is-depression-just-bad-chemistry/
3. http://roar.uel.ac.uk/7402/
4. RCPsych survey (now deleted)
5. https://www.psychologytoday.com/gb/blog/side-effects/201107/antidepressantwithdrawal-syndrome
6. http://time.com/3399344/antidepressant-changes-the-brain-study-finds/
7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118946/
8. http://roar.uel.ac.uk/7402/
9. https://www.karger.com/Article/FullText/370338
10.http://www.stacommunications.com/journals/diagnosis/2006/Diagnosis_sep_06/DS.pdf
www.jfmoore.co.uk August, 2018

What we know about antidepressant withdrawal V1

James Moore

BBC File on Four program on Antidepressants in Children

A recent BBC File on Four program on Antidepressants in Children, presented by Paul Connolly, has drawn disparaging comments on posts here. Here is some background detail. I was interviewed for the program. My messages were as follows:

  1. That the trials of Prozac in children were identical to the trials of other SSRIs and other antidepressant drugs in this age group – negative. There are more negative Prozac trials for depression in this age group than for any other antidepressant.
  2. Part of our problem s that MHRA and NICE don’t want to be seen to go back on judgements they made 14 years ago when they licensed Prozac. Better children die than regulators lose face.
  3. That all of the literature in this area is ghost or company written.
  4. That there is no access to data from clinical trials – MHRA don’t have access, NICE don’t have access – no-one does.

It was clear to me that Paul Connolly, although expressing shock just like Chris van Tulleken some months before at what I laid out, was not going to include this material. Chris was somewhat the braver of the two. He rather subtly skewered NICE – but probably too subtle for most people. A week before the programme ran, there was an email from File on Four saying that owing to space constraints I was one of several people being omitted.

What File on Four ended up was a combination of the irritatingly anodyne and bizarre. What is the definitive answer about whether antidepressants work, Paul Connolly asked – no one knows he said. There are definitive answers the public deserve to be told about but FoF bottled it. Doctors are all at the mercy of clinical trials, he said, before turning to Ian Goodyer, someone who has pushed antidepressants for children for years who said on the basis of the biggest trials with 475 children he could tell us that fluoxetine (Prozac) worked in 67% of cases rising to 80+ %. I’d fail a medical student who offered me this answer if presented with the results of the TADS trial – the one Goodyer was talking about. There is no good evidence fluoxetine worked in this trial. Goodyer omitted to tell us that there were 34 suicidal events on fluoxetine compared to 3 on placebo. Goodyer made something of the fact this was the biggest trial of Prozac which sounds good but isn’t the biggest – not by a longshot. Even if it were the biggest, Goodyer fails to appreciate that the bigger the trial the greater the chance you can show snake oil works. If drugs are worth it, small trials are all that is needed. Prozac, fluoxetine, is in fact the drug with more negative trials than any other. These points are irritating. The bizarre one was that FoF made Andrea Cipriani out to be the radical outlying voice. AC’s work is totally controlled by industry – he knows he has no access to the data and his work is based on ghostwritten or company written reports . He’s a very nice man but the idea that he is a voice for caution as regards the use of antidepressants is bizarre.

Read the full article

The needs of the older generation being met by prescribed medication?

I’m a great believer in respecting our elders and them passing on their knowledge and experience to help us get on in life. Yes, many have outdated ideas or perceptions of “the youth today” and have old fashioned values. But they are still here, many into their 80’s and 90’s. Many are fitter than us mid lifers. So why is it that as soon as you are 65 or pensionable age, you are considered by current legislation, an older person. That’s the age we should start to decline, shouldn’t be working or maybe not long on this mortal coil?

We may have reasonable health and fitness most of our working life but it’s at this point, earlier for some and much later for others, that especially after retirement, we “start to fall apart”. The mind set for many?

All the education we have about getting older gracefully, keep active physically or mentally, something kicks in and we start to have “problems”.

Many are lucky and can keep going but with many more this mind set of getting older brings on comparing ailments and frequent trips to the surgery and with it automatic prescriptions. We’ve been used to being prescribed medication throughout our years but usually only short term, 1 week, a month. But as we get older the prescriptions are ongoing, repeated every month, without need to see a doctor. Yes they have reviews but how many people remember how they felt before being prescribed. Some even admit to not following their medication guidelines.

It seems standard that most have at least 4 prescribed meds. Ailments usually arthritis, high blood pressure, heart problems, diabetes and more often than not, have been victim of a stroke. May have only been a TIA, but medication suddenly gets tripled and doesn’t get questioned. A few do look at their life style and diet so as to refrain from having to take anything, but most accept they are getting older and increased medication comes with the territory.

In my work I have met people who will not go to have their cataracts removed or go for that hearing test their children keep on at them about, but will accept the side effects from the multiple medications they are on. This is often out of fear that something will go wrong or that they’ll seem like an elderly person. Yet unknowing either having more health problems as a result of long term use or becoming addicted to certain medication.

What are our older population being prescribed? How do we know which are not appropriate for elderly use. Some antipsychotic drugs may not be appropriate for our older population with dementia especially women as can worsen confusion. Some drugs can have adverse effects or even have no effect at all due to long term usage.

When visiting our local surgeries, we never get to see our doctor anymore. It could be another partner or a locum. All experienced and qualified, but may not know our history. When discharged from hospital, additional medication is prescribed. More work is needed to educate our older trusting more vulnerable members of our communities to ensure their medication is appropriate, in date, not counter active to other medication prescribed and most important, the side effects are not going to be life threatening.

Further reading

https://www.express.co.uk/life-style/health/389014/Fears-over-lazy-GPs-prescribing-strong-sleeping-pills-to-elderly

https://www.msdmanuals.com/en-gb/home/older-people%E2%80%99s-health-issues/aging-and-drugs/aging-and-drugs

(C.W. actively works to ensure that all older people are safe, secure and their needs are appropriately met.)